Across TCGA patient cohorts, SPDYE18 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,181 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPDYE18-associated proteins across cancer lineages are DNAJC1, GTF2I, and VEZF1. Each is linked with SPDYE18 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPDYE18-to-partner and partner-to-SPDYE18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE18→partner) and Y-score (partner→SPDYE18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DNAJC1 →	-0.435	-0.464	<.001	<.001	3	5
GBM	GTF2I →	+0.484	+0.453	<.001	.001	3	5
GBM	VEZF1 →	+0.505	+0.435	<.001	.001	3	4
BRCA	ASCC2 →	-0.175	-0.438	.007	.002	3	4
PDAC	CUX1_S1069 →	+0.649	+0.434	<.001	<.001	3	4
HNSC	ING4 →	+0.458	+0.969	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,181 associations by consensus.

Exploration

SPDYE18 survival (RNA) · tumor vs normal (RNA) · all SPDYE18 data types