Across TCGA patient cohorts, SPDYE17 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,063 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPDYE17-associated proteins across cancer lineages are TSC2_S664, BAG4_S179, and ARVCF_S864. Each is linked with SPDYE17 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPDYE17-to-partner and partner-to-SPDYE17 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE17→partner) and Y-score (partner→SPDYE17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TSC2_S664 →	-0.420	-0.165	<.001	<.001	3	3
PDAC	BAG4_S179 →	+0.826	+0.153	.004	.004	3	3
LUAD	ARVCF_S864 →	+0.735	+0.235	.007	.003	3	2
PDAC	RPS3A_S263 →	-0.238	-0.166	.005	.003	3	2
OV	RRP8_S106 →	-1.388	-0.364	<.001	.001	3	2
HNSC	RSBN1L →	+0.320	+0.680	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,063 associations by consensus.

Exploration

SPDYE17 survival (RNA) · tumor vs normal (RNA) · all SPDYE17 data types