Across TCGA patient cohorts, SPDYC RNA expression is significantly associated with the go_rna of many other GO terms, with 6,956 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible SPDYC-associated GO terms across cancer lineages are Protein maturation by [4Fe-4S] cluster transfer, Thioester metabolic process, and DNA conformation change. Each is linked with SPDYC in more than 12 cancer types. Because this analysis shows association rather than direction, both SPDYC-to-partner and partner-to-SPDYC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYC→partner) and Y-score (partner→SPDYC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Protein maturation by [4Fe-4S] cluster transfer →	+0.051	+0.281	.003	.001	2	13
CHOL	Thioester metabolic process →	+0.038	+0.837	.003	.002	3	11
TGCT	DNA conformation change →	+0.031	+1.085	<.001	<.001	3	11
ESCA	Regulation of meiotic cell cycle phase transition →	+0.054	+1.048	<.001	<.001	2	12
LIHC	Amino acid catabolic process →	+0.033	+0.708	<.001	<.001	3	11
LUSC	Regulation of DNA-directed DNA polymerase activity →	+0.046	+0.567	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,956 associations by consensus.

Exploration

SPDYC survival (RNA) · tumor vs normal (RNA) · all SPDYC data types