SPDYC

RNA expression — cross-omics
Cross-omicsRNA → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SPDYC RNA expression is significantly associated with the RNA expression of many other genes, with 2,826 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPDYC-associated genes across cancer lineages are HMBS, DHRS11, and TMC5. Each is linked with SPDYC in more than 1 cancer types. Because this analysis shows association rather than direction, both SPDYC-to-partner and partner-to-SPDYC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYC→partner) and Y-score (partner→SPDYC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaHMBS →+1.008+1.179<.001<.00132
BLOOD_LeukemiaDHRS11 →+0.965+1.140<.001<.00132
STOMACHTMC5 →+3.353+0.759<.001<.00132
BLOOD_LeukemiaRGL1 →-1.062-0.713<.001<.00132
BLOOD_LeukemiaVLDLR →-1.536-0.913.001.00132
BLOOD_LeukemiaFRRS1 →+1.361+1.135<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,826 associations by consensus.

Exploration