SPCS2P4

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPCS2P4 RNA expression is significantly associated with the mutation status of many other genes, with 9,732 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPCS2P4-associated genes across cancer lineages are CDH6, PTPRC, and TG. Each is linked with SPCS2P4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPCS2P4-to-partner and partner-to-SPCS2P4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPCS2P4→partner) and Y-score (partner→SPCS2P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCDH6 →+3.828+0.695<.001<.00134
SKCMPTPRC →+1.636+0.276.004.00434
UCECTG →+1.243+0.350.001<.00134
LGGCIC →+1.841+0.317<.001<.00133
KIRCPBRM1 →+1.654+0.269<.001.00333
LIHCFUT9 →+2.087+0.395.005.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,732 associations by consensus.

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