SPCS2P3

Across TCGA patient cohorts, SPCS2P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,544 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPCS2P3-associated GO terms across cancer lineages are Regulation of DNA repair, Positive regulation of DNA metabolic process, and Peptidyl-lysine modification. Each is linked with SPCS2P3 in more than 21 cancer types. Because this analysis shows association rather than direction, both SPCS2P3-to-partner and partner-to-SPCS2P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by SPCS2P3-low versus SPCS2P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPCS2P3→partner) and Y-score (partner→SPCS2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA repair →	+0.038	+0.096	<.001	<.001	3	21
ESCA	Positive regulation of DNA metabolic process →	+0.061	+0.166	.003	<.001	1	22
STAD	Peptidyl-lysine modification →	+0.038	+0.096	<.001	<.001	3	20
STAD	tRNA metabolic process →	+0.041	+0.127	<.001	<.001	3	20
STAD	Mitochondrial gene expression →	+0.045	+0.111	<.001	<.001	3	19
STAD	Regulation of double-strand break repair →	+0.038	+0.082	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,544 associations by consensus.

Regulation of DNA repair by SPCS2P3 expression — STAD

Explore this box plot interactively →