SPC24

Across TCGA patient cohorts, SPC24 RNA expression is significantly associated with the protein abundance of many other proteins, with 26,270 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPC24-associated proteins across cancer lineages are BUB1B_S543, CDC20_T70, and CDK1. Each is linked with SPC24 in more than 9 cancer types. Because this analysis shows association rather than direction, both SPC24-to-partner and partner-to-SPC24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPC24 versus BUB1B_S543 in UCEC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPC24→partner) and Y-score (partner→SPC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BUB1B_S543 →	+1.019	+1.386	<.001	<.001	3	10
LUAD	CDC20_T70 →	+1.173	+1.082	<.001	<.001	3	10
LUAD	CDK1 →	+0.929	+1.161	<.001	<.001	3	10
LUAD	ECT2_T359 →	+1.480	+1.220	<.001	<.001	3	10
LSCC	FEN1 →	+0.567	+0.958	<.001	<.001	3	10
LUAD	NCAPD2 →	+0.775	+1.231	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,270 associations by consensus.

SPC24 vs BUB1B_S543 — UCEC

Explore this scatter interactively →