Across TCGA patient cohorts, SPATS2L protein abundance is significantly associated with the RNA expression of many other genes, with 13,960 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPATS2L-associated genes across cancer lineages are SRPX2, CALD1, and COL8A1. Each is linked with SPATS2L in more than 6 cancer types. Because this analysis shows association rather than direction, both SPATS2L-to-partner and partner-to-SPATS2L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATS2L→partner) and Y-score (partner→SPATS2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SRPX2 →	+1.085	+0.454	<.001	<.001	3	7
OV	CALD1 →	+1.198	+0.436	<.001	<.001	3	7
OV	COL8A1 →	+1.971	+0.439	<.001	<.001	3	7
BRCA	GPX8 →	+0.979	+0.441	<.001	<.001	3	7
OV	CTHRC1 →	+1.694	+0.437	<.001	<.001	3	7
OV	AXL →	+0.818	+0.376	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,960 associations by consensus.

Exploration

SPATS2L survival (RNA) · tumor vs normal (RNA) · all SPATS2L data types