SPATS2

Across TCGA cell cohorts, SPATS2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SPATS2-associated genes across cancer lineages are SERPINA7, C1orf158, and OR2T35. Each is linked with SPATS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATS2-to-partner and partner-to-SPATS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA7 grouped by SPATS2-low versus SPATS2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATS2→partner) and Y-score (partner→SPATS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SERPINA7 →	+0.459	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1orf158 →	+0.053	+4.807	<.001	.006	3	1
BLOOD_Myeloma	OR2T35 →	+0.086	+4.807	<.001	.006	3	1
LARGE_INTESTINE	SLC17A6 →	+0.023	+4.977	<.001	.007	3	1
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1
OVARY	C12orf40 →	+0.011	+4.029	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

SERPINA7 by SPATS2 expression — BLOOD_Myeloma

Explore this box plot interactively →