SPATC1L

Across TCGA pan-cancer cohorts, SPATC1L Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SPATC1L data layer compared with 23 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher SPATC1L Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SPATC1L expression acts as an unfavorable survival marker.

SARC, COAD, and ACC are the cancer types where SPATC1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SARC	DFS	Median	All	0.179	0.612	.024	6	view →
COAD	OS	Median	III,IV	0.159	0.692	.021	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SPATC1L–SARC (DFS)

Open the SARC breakdown →