Across TCGA patient cohorts, SPATC1L RNA expression is significantly associated with the go_rna of many other GO terms, with 7,019 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SPATC1L-associated GO terms across cancer lineages are Positive regulation of protein kinase A signaling, Regulation of protein kinase A signaling, and tRNA thio-modification. Each is linked with SPATC1L in more than 20 cancer types. Because this analysis shows association rather than direction, both SPATC1L-to-partner and partner-to-SPATC1L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATC1L→partner) and Y-score (partner→SPATC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Positive regulation of protein kinase A signaling →	+0.113	+1.085	<.001	<.001	3	21
CHOL	Regulation of protein kinase A signaling →	+0.075	+1.282	<.001	<.001	3	17
PAAD	tRNA thio-modification →	+0.045	+0.686	<.001	<.001	3	15
DLBC	[4Fe-4S] cluster assembly →	+0.061	+0.954	<.001	<.001	2	16
HNSC	Regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator →	+0.042	+0.691	<.001	<.001	3	13
DLBC	Medium-chain fatty acid catabolic process →	-0.072	-0.780	.002	.005	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,019 associations by consensus.

Exploration

SPATC1L survival (RNA) · tumor vs normal (RNA) · all SPATC1L data types