SPATC1L

Across TCGA cell cohorts, SPATC1L mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPATC1L-associated genes across cancer lineages are CD300H, OR13C4, and SLC32A1. Each is linked with SPATC1L in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATC1L-to-partner and partner-to-SPATC1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by SPATC1L-low versus SPATC1L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATC1L→partner) and Y-score (partner→SPATC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1
LUNG_SCLC	OR13C4 →	+0.165	+5.029	<.001	.006	3	1
BLOOD_Leukemia	SLC32A1 →	+0.577	+3.901	<.001	.006	3	1
BLOOD_Leukemia	GML →	+0.098	+4.567	<.001	.001	3	1
BLOOD_Leukemia	IL17F →	+0.038	+3.855	.009	.007	3	1
BLOOD_Leukemia	C20orf85 →	+0.018	+4.384	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

CD300H by SPATC1L expression — LARGE_INTESTINE

Explore this box plot interactively →