Across TCGA cell cohorts, SPATC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,091 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPATC1-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Metanephric proximal tubule development, and Positive regulation of cation transmembrane transport. Each is linked with SPATC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SPATC1-to-partner and partner-to-SPATC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATC1→partner) and Y-score (partner→SPATC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.168	+0.296	<.001	.002	3	11
BONE	Metanephric proximal tubule development →	+0.270	+0.265	<.001	<.001	3	10
PANCREAS	Positive regulation of cation transmembrane transport →	-0.120	-0.149	<.001	<.001	3	10
LIVER	Positive regulation of monoatomic ion transmembrane transport →	-0.121	-0.131	<.001	.002	3	10
OESOPHAGUS	Positive regulation of translation →	+0.072	+0.371	.002	.003	3	9
BREAST	Cellular detoxification of methylglyoxal →	+0.113	+0.348	.002	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,091 associations by consensus.

Exploration

SPATC1 survival (RNA) · tumor vs normal (RNA) · all SPATC1 data types