SPATA9

Across TCGA cell cohorts, SPATA9 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SPATA9-associated genes across cancer lineages are BPIFB6, ACER1, and TECRL. Each is linked with SPATA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA9-to-partner and partner-to-SPATA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB6 grouped by SPATA9-low versus SPATA9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA9→partner) and Y-score (partner→SPATA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1
LARGE_INTESTINE	ACER1 →	+0.105	+3.823	<.001	.006	3	1
LARGE_INTESTINE	TECRL →	+0.017	+4.562	<.001	<.001	3	1
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

BPIFB6 by SPATA9 expression — LARGE_INTESTINE

Explore this box plot interactively →