Across TCGA patient cohorts, SPATA8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,381 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPATA8-associated GO terms across cancer lineages are Positive regulation of epithelial cell migration, Regulation of protein maturation, and Retina vasculature development in camera-type eye. Each is linked with SPATA8 in more than 11 cancer types. Because this analysis shows association rather than direction, both SPATA8-to-partner and partner-to-SPATA8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA8→partner) and Y-score (partner→SPATA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of epithelial cell migration →	+0.038	+0.065	<.001	<.001	3	12
STAD	Regulation of protein maturation →	+0.053	+0.084	<.001	<.001	3	12
TGCT	Retina vasculature development in camera-type eye →	+0.079	+0.666	<.001	<.001	3	12
TGCT	Regulation of epithelial cell migration →	+0.047	+0.728	<.001	<.001	3	12
STAD	Negative regulation of DNA-binding transcription factor activity →	+0.027	+0.052	<.001	<.001	3	12
TGCT	Regulation of transmembrane receptor protein serine/threonine kinase signaling pathway →	+0.038	+0.570	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,381 associations by consensus.

Exploration

SPATA8 survival (RNA) · tumor vs normal (RNA) · all SPATA8 data types