SPATA6

Across TCGA cell cohorts, SPATA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,677 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SPATA6-associated GO terms across cancer lineages are Cytoskeleton-dependent intracellular transport, Intraciliary anterograde transport, and Protein localization to cilium. Each is linked with SPATA6 in more than 12 cancer types. Because this analysis shows association rather than direction, both SPATA6-to-partner and partner-to-SPATA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent intracellular transport grouped by SPATA6-low versus SPATA6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA6→partner) and Y-score (partner→SPATA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytoskeleton-dependent intracellular transport →	+0.049	+1.177	.004	<.001	3	13
LUNG_NSCLC_LUSC	Intraciliary anterograde transport →	+0.098	+1.061	.001	.005	3	13
BREAST	Protein localization to cilium →	+0.066	+1.047	<.001	<.001	3	13
LUNG_NSCLC_LUAD	Intraciliary retrograde transport →	+0.080	+0.757	<.001	.001	3	12
BLOOD_Lymphoma	Establishment of protein localization to organelle →	+0.055	+0.537	<.001	.001	3	12
BONE	Transport along microtubule →	+0.050	+1.083	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,677 associations by consensus.

Cytoskeleton-dependent intracellular transport by SPATA6 expression — BONE

Explore this box plot interactively →