SPATA5L1

Across TCGA patient cohorts, SPATA5L1 mutation is significantly associated with the RNA expression of many other genes, with 3,035 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA5L1-associated genes across cancer lineages are RN7SL402P, RNU7-148P, and OR9Q2. Each is linked with SPATA5L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPATA5L1-to-partner and partner-to-SPATA5L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL402P grouped by SPATA5L1-low versus SPATA5L1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA5L1→partner) and Y-score (partner→SPATA5L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL402P →	+0.120	+2.743	<.001	.008	3	3
SKCM	RNU7-148P →	+0.169	+4.485	<.001	.004	3	2
COAD	OR9Q2 →	+0.044	+4.721	<.001	.004	3	2
COAD	SUMO2P5 →	+0.161	+5.409	.001	.001	3	2
UCEC	SNRPGP17 →	+0.222	+2.031	.004	.002	3	2
UCEC	RPL23AP90 →	+0.313	+2.156	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,035 associations by consensus.

RN7SL402P by SPATA5L1 expression — SKCM

Explore this box plot interactively →