SPATA5L1

Across TCGA cell cohorts, SPATA5L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,855 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPATA5L1-associated GO terms across cancer lineages are Circadian sleep/wake cycle, De novo centriole assembly, and Regulation of cell cycle checkpoint. Each is linked with SPATA5L1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SPATA5L1-to-partner and partner-to-SPATA5L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Circadian sleep/wake cycle grouped by SPATA5L1-low versus SPATA5L1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA5L1→partner) and Y-score (partner→SPATA5L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Circadian sleep/wake cycle →	+0.198	+0.694	.005	.001	3	14
LUNG_NSCLC_LUSC	De novo centriole assembly →	+0.133	+0.542	<.001	.003	3	12
OESOPHAGUS	Regulation of cell cycle checkpoint →	+0.100	+0.506	<.001	.007	3	12
BONE	Nucleic acid transport →	+0.103	+0.615	<.001	<.001	3	12
BONE	RNA transport →	+0.103	+0.615	<.001	<.001	3	12
BONE	Establishment of RNA localization →	+0.099	+0.553	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,855 associations by consensus.

Circadian sleep/wake cycle by SPATA5L1 expression — LIVER

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