SPATA5

Across TCGA patient cohorts, SPATA5 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,179 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPATA5-associated proteins across cancer lineages are HPF1, MAD2L1, and MCM2_S27. Each is linked with SPATA5 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPATA5-to-partner and partner-to-SPATA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATA5 versus HPF1 in LSCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA5→partner) and Y-score (partner→SPATA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HPF1 →	+0.377	+0.472	<.001	<.001	3	7
UCEC	MAD2L1 →	+0.617	+0.448	<.001	<.001	3	7
LSCC	MCM2_S27 →	+0.774	+0.569	<.001	<.001	3	6
GBM	CTDSPL2 →	+0.407	+0.321	<.001	<.001	3	6
GBM	WIZ →	+0.382	+0.380	<.001	<.001	3	5
LSCC	WRNIP1 →	+0.421	+0.516	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,179 associations by consensus.

SPATA5 vs HPF1 — LSCC

Explore this scatter interactively →