Across TCGA patient cohorts, SPATA45 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,048 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPATA45-associated GO terms across cancer lineages are IRES-dependent viral translational initiation, Mitochondrial respiratory chain complex assembly, and Establishment of protein localization to chromosome. Each is linked with SPATA45 in more than 15 cancer types. Because this analysis shows association rather than direction, both SPATA45-to-partner and partner-to-SPATA45 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA45→partner) and Y-score (partner→SPATA45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	IRES-dependent viral translational initiation →	+0.094	+0.469	<.001	<.001	3	16
STAD	Mitochondrial respiratory chain complex assembly →	+0.053	+0.375	<.001	<.001	3	16
ESCA	Establishment of protein localization to chromosome →	+0.066	+0.331	.002	.001	3	15
STAD	Cytoplasmic translation →	+0.069	+0.347	<.001	<.001	3	15
ESCA	Tetrapyrrole biosynthetic process →	+0.058	+0.377	.002	<.001	3	15
TGCT	Sequestering of iron ion →	+0.088	+0.357	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,048 associations by consensus.

Exploration

SPATA45 survival (RNA) · tumor vs normal (RNA) · all SPATA45 data types