SPATA31D5P

Across TCGA pan-cancer cohorts, SPATA31D5P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SPATA31D5P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SPATA31D5P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SPATA31D5P is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

KIRC, ESCA, and BRCA are the cancer types where SPATA31D5P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPATA31D5P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.003	.007	4	view →
ESCA	All	II,III,IV	+0.024	.037	2	view →
BRCA	All	III,IV	−0.008	.024	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SPATA31D5P–KIRC

Open the KIRC breakdown →