SPATA31C1

Across TCGA patient cohorts, SPATA31C1 mutation is significantly associated with the RNA expression of many other genes, with 1,992 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA31C1-associated genes across cancer lineages are RPL23AP82, RPL35P8, and RNU6-701P. Each is linked with SPATA31C1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPATA31C1-to-partner and partner-to-SPATA31C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP82 grouped by SPATA31C1-low versus SPATA31C1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31C1→partner) and Y-score (partner→SPATA31C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL23AP82 →	+0.443	+1.743	.002	.004	3	4
CESC	RPL35P8 →	+0.200	+4.035	<.001	.003	3	3
BLCA	RNU6-701P →	+0.163	+3.251	.002	.007	3	3
READ	P4HA3-AS1 →	+0.033	+4.202	.001	.008	3	3
READ	MIR4774 →	+0.627	+5.257	<.001	.002	3	3
UCEC	PHF5A →	+0.326	+2.098	.008	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,992 associations by consensus.

RPL23AP82 by SPATA31C1 expression — SKCM

Explore this box plot interactively →