SPATA31A7

Across TCGA patient cohorts, SPATA31A7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,456 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPATA31A7-associated GO terms across cancer lineages are SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, Protein destabilization, and Telomerase RNA localization. Each is linked with SPATA31A7 in more than 7 cancer types. Because this analysis shows association rather than direction, both SPATA31A7-to-partner and partner-to-SPATA31A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process grouped by SPATA31A7-low versus SPATA31A7-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A7→partner) and Y-score (partner→SPATA31A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.062	+0.014	<.001	<.001	3	8
STAD	Protein destabilization →	+0.076	+0.011	<.001	<.001	3	7
STAD	Telomerase RNA localization →	+0.099	+0.017	<.001	<.001	2	8
STAD	Mitotic spindle assembly →	+0.101	+0.011	<.001	<.001	3	7
STAD	Negative regulation of cell cycle G2/M phase transition →	+0.090	+0.015	<.001	<.001	3	7
STAD	Recombinational repair →	+0.085	+0.012	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,456 associations by consensus.

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process by SPATA31A7 expression — STAD

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