SPATA31A7

Across TCGA patient cohorts, SPATA31A7 mutation is significantly associated with the RNA expression of many other genes, with 230 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA31A7-associated genes across cancer lineages are PLSCR5-AS1, RNA5SP57, and MIR3912. Each is linked with SPATA31A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA31A7-to-partner and partner-to-SPATA31A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLSCR5-AS1 grouped by SPATA31A7-low versus SPATA31A7-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A7→partner) and Y-score (partner→SPATA31A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	PLSCR5-AS1 →	+0.084	+7.640	<.001	.009	3	2
LUAD	RNA5SP57 →	+0.412	+5.155	<.001	.002	3	2
LUAD	MIR3912 →	+0.609	+3.855	<.001	.006	3	2
UCEC	PSG9 →	+0.102	+3.820	<.001	<.001	3	1
UCEC	LILRP1 →	+0.104	+2.377	.006	.009	3	1
UCEC	BNIP3P1 →	+0.647	+3.354	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 230 associations by consensus.

PLSCR5-AS1 by SPATA31A7 expression — BLCA

Explore this box plot interactively →