SPATA31A7

Across TCGA patient cohorts, SPATA31A7 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA31A7-associated genes across cancer lineages are Platelets, lymphatic Endothelial cells, and pDC. Each is linked with SPATA31A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA31A7-to-partner and partner-to-SPATA31A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by SPATA31A7-low versus SPATA31A7-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A7→partner) and Y-score (partner→SPATA31A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Platelets →	+0.027	+3.727	<.001	.046	3	1
UCEC	lymphatic Endothelial cells →	-0.025	-3.129	.044	.019	3	1
UCEC	pDC →	+0.061	+3.008	.016	.019	3	1
UCEC	Th2 cells →	+0.203	+2.815	.032	.036	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Platelets by SPATA31A7 expression — LUSC

Explore this box plot interactively →