SPATA31A3

Across TCGA patient cohorts, SPATA31A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,707 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPATA31A3-associated GO terms across cancer lineages are Microtubule polymerization or depolymerization, Positive regulation of chromosome organization, and Nuclear-transcribed mRNA catabolic process. Each is linked with SPATA31A3 in more than 9 cancer types. Because this analysis shows association rather than direction, both SPATA31A3-to-partner and partner-to-SPATA31A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization or depolymerization grouped by SPATA31A3-low versus SPATA31A3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A3→partner) and Y-score (partner→SPATA31A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Microtubule polymerization or depolymerization →	+0.084	+0.010	<.001	<.001	3	10
STAD	Positive regulation of chromosome organization →	+0.104	+0.011	<.001	<.001	3	9
STAD	Nuclear-transcribed mRNA catabolic process →	+0.097	+0.010	<.001	<.001	3	9
STAD	Mitotic spindle assembly →	+0.112	+0.010	<.001	<.001	3	9
STAD	Cytoskeleton-dependent intracellular transport →	+0.074	+0.011	<.001	<.001	3	9
STAD	Regulation of microtubule polymerization or depolymerization →	+0.076	+0.010	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,707 associations by consensus.

Microtubule polymerization or depolymerization by SPATA31A3 expression — STAD

Explore this box plot interactively →