SPATA31A3

Across TCGA cell cohorts, SPATA31A3 RNA expression is significantly associated with the mutation status of many other genes, with 41 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SPATA31A3-associated genes across cancer lineages are PTPRZ1, GSDMD, and ZNF142. Each is linked with SPATA31A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA31A3-to-partner and partner-to-SPATA31A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTPRZ1 grouped by SPATA31A3-low versus SPATA31A3-high in OVARY.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A3→partner) and Y-score (partner→SPATA31A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PTPRZ1 →	+3.754	+0.013	.002	<.001	3	2
URINARY_TRACT	GSDMD →	+4.584	+0.011	.002	.001	3	1
URINARY_TRACT	ZNF142 →	+3.584	+0.009	.005	.007	3	1
URINARY_TRACT	MT-ND1 →	+3.584	+0.009	.005	.007	3	1
PANCREAS	PRR12 →	+3.201	+0.014	.008	.001	3	1
PANCREAS	CEP350 →	+3.201	+0.017	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

PTPRZ1 by SPATA31A3 expression — OVARY

Explore this box plot interactively →