Across TCGA patient cohorts, SPATA31A1 mutation is significantly associated with the RNA expression of many other genes, with 4,263 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA31A1-associated genes across cancer lineages are PPM1G, PIMREG, and TACC3. Each is linked with SPATA31A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPATA31A1-to-partner and partner-to-SPATA31A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A1→partner) and Y-score (partner→SPATA31A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PPM1G →	+0.417	+2.220	<.001	<.001	3	5
LUAD	PIMREG →	+0.827	+4.333	.001	<.001	3	5
UCEC	TACC3 →	+0.583	+2.192	<.001	<.001	3	5
UCEC	UBE2S →	+0.525	+2.758	.002	<.001	3	4
SKCM	ZWINT →	+0.645	+3.845	<.001	<.001	3	4
SKCM	TOMM40 →	+0.507	+2.233	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,263 associations by consensus.

Exploration

SPATA31A1 survival (RNA) · tumor vs normal (RNA) · all SPATA31A1 data types