Across TCGA patient cohorts, SPATA31A1 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA31A1-associated genes across cancer lineages are FoxM1, Cyclin-B1, and PCNA. Each is linked with SPATA31A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPATA31A1-to-partner and partner-to-SPATA31A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA31A1→partner) and Y-score (partner→SPATA31A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FoxM1 →	+0.255	+3.807	.021	<.001	1	5
UCEC	Cyclin-B1 →	+0.615	+3.087	<.001	<.001	3	3
UCEC	PCNA →	+0.248	+1.947	<.001	<.001	3	2
UCEC	14-3-3_beta →	-0.091	-2.143	.003	.002	3	2
UCEC	p62 Lck ligand →	+0.438	+2.222	<.001	<.001	3	2
UCEC	TIGAR →	+0.112	+1.090	.016	.032	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

SPATA31A1 survival (RNA) · tumor vs normal (RNA) · all SPATA31A1 data types