SPATA22

Across TCGA patient cohorts, SPATA22 protein abundance is significantly associated with the RNA expression of many other genes, with 248 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPATA22-associated genes across cancer lineages are NEFH, LACTB, and ZNF200. Each is linked with SPATA22 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA22-to-partner and partner-to-SPATA22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATA22 versus NEFH in UCEC, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA22→partner) and Y-score (partner→SPATA22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NEFH →	-1.607	-1.866	.001	.002	3	1
UCEC	LACTB →	+0.724	+1.938	.003	.001	3	1
UCEC	ZNF200 →	+0.613	+1.785	.002	.006	3	1
UCEC	AGR2 →	+2.719	+1.598	.004	.005	3	1
UCEC	SLC35F2 →	+1.262	+1.901	.004	.002	3	1
UCEC	PCDHB3 →	-2.303	-2.254	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 248 associations by consensus.

SPATA22 vs NEFH — UCEC

Explore this scatter interactively →