SPATA22

Across TCGA cell cohorts, SPATA22 RNA expression is significantly associated with the go_rna of many other GO terms, with 209 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SPATA22-associated GO terms across cancer lineages are Regulation of dopamine receptor signaling pathway, Heme catabolic process, and Ribonucleoside catabolic process. Each is linked with SPATA22 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPATA22-to-partner and partner-to-SPATA22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of dopamine receptor signaling pathway grouped by SPATA22-low versus SPATA22-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA22→partner) and Y-score (partner→SPATA22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of dopamine receptor signaling pathway →	-0.138	-0.664	<.001	.002	3	3
SOFT_TISSUE	Heme catabolic process →	-0.185	-1.181	<.001	.002	3	2
SOFT_TISSUE	Ribonucleoside catabolic process →	-0.131	-0.928	.005	.002	3	2
SOFT_TISSUE	Regulation of mRNA stability →	+0.044	+0.616	.001	.004	3	2
SOFT_TISSUE	Pigment catabolic process →	-0.185	-1.181	<.001	.002	3	2
SOFT_TISSUE	Platelet dense granule organization →	+0.047	+0.643	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 209 associations by consensus.

Regulation of dopamine receptor signaling pathway by SPATA22 expression — SOFT_TISSUE

Explore this box plot interactively →