Across TCGA patient cohorts, SPATA21 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,373 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPATA21-associated proteins across cancer lineages are NIPBL, PHF8_S857, and RAD21. Each is linked with SPATA21 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPATA21-to-partner and partner-to-SPATA21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA21→partner) and Y-score (partner→SPATA21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NIPBL →	+0.193	+0.328	<.001	<.001	3	4
HNSC	PHF8_S857 →	+0.427	+0.503	.002	<.001	3	4
GBM	RAD21 →	+0.391	+0.337	<.001	<.001	3	4
LSCC	RBMX_S352 →	+0.642	+0.275	<.001	<.001	3	4
GBM	GABPA →	+0.301	+0.291	<.001	<.001	3	4
GBM	GATAD2B_S334 →	+0.453	+0.268	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,373 associations by consensus.

Exploration

SPATA21 survival (RNA) · tumor vs normal (RNA) · all SPATA21 data types