Across TCGA patient cohorts, SPATA21 protein abundance is significantly associated with the RNA expression of many other genes, with 299 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SPATA21-associated genes across cancer lineages are PYGL, PSMA7, and PGK1. Each is linked with SPATA21 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA21-to-partner and partner-to-SPATA21 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA21→partner) and Y-score (partner→SPATA21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PYGL →	+1.066	+2.703	.003	.003	3	1
PDAC	PSMA7 →	+0.609	+2.703	<.001	.003	3	1
PDAC	PGK1 →	+1.453	+2.703	.007	.003	3	1
PDAC	NDRG1 →	+1.863	+2.703	.001	.003	3	1
PDAC	GPI →	+1.063	+2.703	.001	.003	3	1
PDAC	DMAC2 →	+0.750	+2.703	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 299 associations by consensus.

Exploration

SPATA21 survival (RNA) · tumor vs normal (RNA) · all SPATA21 data types