Across TCGA cell cohorts, SPATA21 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,584 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPATA21-associated GO terms across cancer lineages are Negative regulation of mRNA splicing, via spliceosome, Metaphase/anaphase transition of mitotic cell cycle, and Negative regulation of DNA-templated transcription initiation. Each is linked with SPATA21 in more than 8 cancer types. Because this analysis shows association rather than direction, both SPATA21-to-partner and partner-to-SPATA21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA21→partner) and Y-score (partner→SPATA21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of mRNA splicing, via spliceosome →	+0.096	+0.131	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Metaphase/anaphase transition of mitotic cell cycle →	+0.139	+0.127	.001	.008	3	9
BONE	Negative regulation of DNA-templated transcription initiation →	+0.109	+0.176	<.001	<.001	3	8
BLOOD_Lymphoma	Negative regulation of RNA splicing →	+0.090	+0.128	<.001	.001	3	8
BONE	Metaphase/anaphase transition of cell cycle →	+0.163	+0.193	.007	<.001	2	9
BLOOD_Lymphoma	Negative regulation of mRNA processing →	+0.093	+0.118	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,584 associations by consensus.

Exploration

SPATA21 survival (RNA) · tumor vs normal (RNA) · all SPATA21 data types