SPATA20

Across TCGA patient cohorts, SPATA20 protein abundance is significantly associated with the RNA expression of many other genes, with 10,162 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPATA20-associated genes across cancer lineages are HOGA1, MEGF9, and TTK. Each is linked with SPATA20 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPATA20-to-partner and partner-to-SPATA20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATA20 versus HOGA1 in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA20→partner) and Y-score (partner→SPATA20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HOGA1 →	+0.673	+0.383	.001	.002	3	5
LSCC	MEGF9 →	+1.183	+0.389	<.001	<.001	3	5
BRCA	TTK →	-1.023	-0.690	<.001	<.001	3	4
BRCA	MASTL →	-0.643	-0.743	<.001	<.001	3	4
BRCA	PIF1 →	-1.127	-0.591	<.001	.002	3	4
UCEC	GEN1 →	-0.494	-0.417	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,162 associations by consensus.

SPATA20 vs HOGA1 — OV

Explore this scatter interactively →