SPATA2

Across TCGA cell cohorts, SPATA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,365 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPATA2-associated GO terms across cancer lineages are Protein linear deubiquitination, Endosomal transport, and Cytosolic transport. Each is linked with SPATA2 in more than 14 cancer types. Because this analysis shows association rather than direction, both SPATA2-to-partner and partner-to-SPATA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear deubiquitination grouped by SPATA2-low versus SPATA2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA2→partner) and Y-score (partner→SPATA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein linear deubiquitination →	+0.422	+0.788	.005	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.055	+0.644	<.001	<.001	3	13
SOFT_TISSUE	Cytosolic transport →	+0.071	+0.710	<.001	<.001	3	13
SOFT_TISSUE	Spliceosomal tri-snRNP complex assembly →	+0.076	+0.582	.003	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Vesicle-mediated transport to the plasma membrane →	+0.069	+0.632	<.001	<.001	3	13
OVARY	IRE1-mediated unfolded protein response →	+0.128	+0.499	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,365 associations by consensus.

Protein linear deubiquitination by SPATA2 expression — SOFT_TISSUE

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