SPATA19

Across TCGA cell cohorts, SPATA19 RNA expression is significantly associated with the mutation status of many other genes, with 205 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPATA19-associated genes across cancer lineages are KRT3, ARID1B, and GRID1. Each is linked with SPATA19 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPATA19-to-partner and partner-to-SPATA19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT3 grouped by SPATA19-low versus SPATA19-high in CNS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA19→partner) and Y-score (partner→SPATA19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	KRT3 →	+4.472	+0.422	.004	<.001	3	3
SKIN	ARID1B →	+3.099	+0.115	.002	<.001	3	3
BLOOD_Myeloma	GRID1 →	+4.807	+0.033	.006	<.001	3	2
KIDNEY	ATP2A3 →	+5.000	+0.036	.005	<.001	3	2
LUNG_SCLC	TEX14 →	+3.256	+0.056	.005	<.001	3	2
BREAST	SNRNP200 →	+4.781	+0.027	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 205 associations by consensus.

KRT3 by SPATA19 expression — CNS

Explore this box plot interactively →