SPATA19

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SPATA19 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SPATA19-associated genes across cancer lineages are CT47A6 and TNP1. Each is linked with SPATA19 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPATA19-to-partner and partner-to-SPATA19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CT47A6 grouped by SPATA19-low versus SPATA19-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA19→partner) and Y-score (partner→SPATA19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCCT47A6 →+1.738+5.029<.001.00631
LARGE_INTESTINETNP1 →+0.128+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CT47A6 by SPATA19 expression — LUNG_SCLC

Box plot of CT47A6 in SPATA19-low vs SPATA19-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration