SPATA18

Across TCGA patient cohorts, SPATA18 protein abundance is significantly associated with the RNA expression of many other genes, with 14,137 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPATA18-associated genes across cancer lineages are RAD51AP1, EZH2, and PRC1. Each is linked with SPATA18 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPATA18-to-partner and partner-to-SPATA18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATA18 versus RAD51AP1 in GBM, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA18→partner) and Y-score (partner→SPATA18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAD51AP1 →	-0.931	-1.204	<.001	<.001	3	7
BRCA	EZH2 →	-0.793	-0.494	<.001	<.001	3	6
GBM	PRC1 →	-0.485	-1.394	<.001	<.001	3	6
GBM	PRC1-AS1 →	-0.618	-1.090	<.001	.001	3	6
GBM	CENPI →	-0.999	-1.230	<.001	.001	3	6
BRCA	CDCA3 →	-1.026	-0.510	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,137 associations by consensus.

SPATA18 vs RAD51AP1 — GBM

Explore this scatter interactively →