SPATA16

Across TCGA cell cohorts, SPATA16 protein abundance is significantly associated with the RNA expression of many other genes, with 1,251 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible SPATA16-associated genes across cancer lineages are MED17, ACTR3B, and DHX9. Each is linked with SPATA16 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPATA16-to-partner and partner-to-SPATA16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPATA16 versus MED17 in KIDNEY, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA16→partner) and Y-score (partner→SPATA16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	MED17 →	+0.699	+1.420	.008	.003	2	5
KIDNEY	ACTR3B →	+1.163	+1.420	.001	.003	3	3
LARGE_INTESTINE	DHX9 →	+0.641	+1.065	<.001	<.001	3	3
LARGE_INTESTINE	CCDC137 →	+0.708	+0.774	<.001	.003	3	3
KIDNEY	LRPPRC →	+0.811	+1.420	.002	.003	3	3
PANCREAS	TMEM177 →	+0.850	+1.238	.008	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,251 associations by consensus.

SPATA16 vs MED17 — KIDNEY

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