Across TCGA pan-cancer cohorts, SPATA12 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SPATA12 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SPATA12 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SPATA12 expression acts as an unfavorable survival marker.

STAD and LIHC are the cancer types where SPATA12 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.096	0.667	<.001	12	view →
LIHC	DFS	Median	All	0.038	0.553	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SPATA12 tumor-vs-normal RNA expression · all SPATA12 data types