SPARCL1

Across TCGA cell cohorts, SPARCL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,232 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPARCL1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of response to endoplasmic reticulum stress, and Response to endoplasmic reticulum stress. Each is linked with SPARCL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SPARCL1-to-partner and partner-to-SPARCL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SPARCL1-low versus SPARCL1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPARCL1→partner) and Y-score (partner→SPARCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.172	+0.621	<.001	<.001	3	6
URINARY_TRACT	Regulation of response to endoplasmic reticulum stress →	+0.077	+0.741	.001	.008	3	6
URINARY_TRACT	Response to endoplasmic reticulum stress →	+0.056	+0.727	.002	.006	3	6
STOMACH	Sodium ion transport →	-0.102	-0.584	<.001	<.001	3	5
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.143	+0.552	<.001	.003	2	6
CNS	Heart trabecula formation →	-0.173	-1.446	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,232 associations by consensus.

Negative regulation of myoblast fusion by SPARCL1 expression — STOMACH

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