Across TCGA patient cohorts, SPANXN4 mutation is significantly associated with the RNA expression of many other genes, with 84 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPANXN4-associated genes across cancer lineages are RNU6-1298P, RBMY3AP, and CPDP1. Each is linked with SPANXN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPANXN4-to-partner and partner-to-SPANXN4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXN4→partner) and Y-score (partner→SPANXN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1298P →	+0.418	+7.741	<.001	.009	3	1
COAD	RBMY3AP →	+0.049	+7.741	<.001	.009	3	1
COAD	CPDP1 →	+0.178	+7.741	<.001	.009	3	1
UCEC	RNA5SP414 →	+0.726	+3.255	<.001	.001	3	1
UCEC	MIR6832 →	+0.876	+3.943	.002	<.001	3	1
UCEC	TXNDC12 →	+0.521	+3.251	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 84 associations by consensus.

Exploration

SPANXN4 survival (RNA) · tumor vs normal (RNA) · all SPANXN4 data types