Across TCGA cell cohorts, SPANXN4 RNA expression is significantly associated with the mutation status of many other genes, with 77 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPANXN4-associated genes across cancer lineages are LOXL4, HERC2, and ZFHX2. Each is linked with SPANXN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPANXN4-to-partner and partner-to-SPANXN4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXN4→partner) and Y-score (partner→SPANXN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	LOXL4 →	+4.867	+0.107	.009	<.001	3	2
SOFT_TISSUE	HERC2 →	+4.930	+0.929	.008	<.001	3	1
SOFT_TISSUE	ZFHX2 →	+3.930	+0.480	.001	<.001	3	1
SOFT_TISSUE	NLRC5 →	+4.930	+0.946	.008	<.001	3	1
SOFT_TISSUE	CYP4B1 →	+4.930	+0.946	.008	<.001	3	1
SOFT_TISSUE	KCNJ1 →	+4.930	+0.929	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

Exploration

SPANXN4 survival (RNA) · tumor vs normal (RNA) · all SPANXN4 data types