Across TCGA patient cohorts, SPANXD RNA expression is significantly associated with the go_rna of many other GO terms, with 4,683 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPANXD-associated GO terms across cancer lineages are Neural tube formation, Regulation of nuclear cell cycle DNA replication, and Response to vitamin. Each is linked with SPANXD in more than 5 cancer types. Because this analysis shows association rather than direction, both SPANXD-to-partner and partner-to-SPANXD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXD→partner) and Y-score (partner→SPANXD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Neural tube formation →	+0.091	+0.135	<.001	<.001	3	6
STAD	Regulation of nuclear cell cycle DNA replication →	+0.072	+0.126	<.001	<.001	3	6
STAD	Response to vitamin →	+0.066	+0.159	<.001	<.001	3	6
STAD	Positive regulation of cell cycle checkpoint →	+0.082	+0.132	<.001	<.001	3	6
STAD	Microtubule depolymerization →	+0.066	+0.157	<.001	<.001	3	6
STAD	Female meiosis chromosome segregation →	+0.099	+0.139	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,683 associations by consensus.

Exploration

SPANXD survival (RNA) · tumor vs normal (RNA) · all SPANXD data types