Across TCGA cell cohorts, SPANXD RNA expression is significantly associated with the go_rna of many other GO terms, with 1,502 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SPANXD-associated GO terms across cancer lineages are Actin filament organization, Regulation of protein localization to mitochondrion, and Maintenance of protein location in cell. Each is linked with SPANXD in more than 7 cancer types. Because this analysis shows association rather than direction, both SPANXD-to-partner and partner-to-SPANXD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXD→partner) and Y-score (partner→SPANXD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Actin filament organization →	+0.144	+1.566	<.001	.004	3	8
SOFT_TISSUE	Regulation of protein localization to mitochondrion →	+0.110	+1.783	<.001	.006	3	7
BONE	Maintenance of protein location in cell →	+0.093	+1.835	.003	.006	3	7
BLOOD_Lymphoma	Protein targeting to ER →	+0.099	+0.032	<.001	.009	3	6
BONE	Regulation of mitochondrial membrane potential →	+0.100	+1.560	<.001	.005	3	6
BONE	Positive regulation of focal adhesion assembly →	+0.213	+1.566	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,502 associations by consensus.

Exploration

SPANXD survival (RNA) · tumor vs normal (RNA) · all SPANXD data types