Across TCGA patient cohorts, SPANXB1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,455 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible SPANXB1-associated genes across cancer lineages are SPANXC, SPANXD, and MAGEC1. Each is linked with SPANXB1 in more than 21 cancer types. Because this analysis shows association rather than direction, both SPANXB1-to-partner and partner-to-SPANXB1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXB1→partner) and Y-score (partner→SPANXB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SPANXC →	+0.919	+1.950	<.001	<.001	3	22
ESCA	SPANXD →	+0.772	+1.561	<.001	<.001	3	19
TGCT	MAGEC1 →	+1.892	+0.911	<.001	<.001	3	18
TGCT	MAGEC2 →	+2.658	+0.911	<.001	<.001	3	17
READ	CSAG4 →	+0.640	+0.423	<.001	<.001	3	15
TGCT	MAGEB6 →	+0.953	+0.725	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,455 associations by consensus.

Exploration

SPANXB1 survival (RNA) · tumor vs normal (RNA) · all SPANXB1 data types