Across TCGA patient cohorts, SPANXB1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,436 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SPANXB1-associated genes across cancer lineages are ZNF862, ZNF827, and ST3GAL2. Each is linked with SPANXB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPANXB1-to-partner and partner-to-SPANXB1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXB1→partner) and Y-score (partner→SPANXB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF862 →	-1.376	-2.491	<.001	.005	3	2
HNSC	ZNF827 →	-1.108	-1.783	.007	.002	3	2
HNSC	ST3GAL2 →	-1.005	-2.186	.008	.003	3	2
LUAD	GTF2IRD2B →	-1.514	-3.085	.002	.002	3	2
LUAD	KCTD7 →	-1.159	-3.144	<.001	.001	3	2
LSCC	CDKN2A →	+2.903	+2.113	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,436 associations by consensus.

Exploration

SPANXB1 survival (RNA) · tumor vs normal (RNA) · all SPANXB1 data types