Across TCGA patient cohorts, SPANXB1 mutation is significantly associated with the RNA expression of many other genes, with 105 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SPANXB1-associated genes across cancer lineages are MIR626, RN7SKP83, and OR13Z1P. Each is linked with SPANXB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPANXB1-to-partner and partner-to-SPANXB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXB1→partner) and Y-score (partner→SPANXB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR626 →	+0.408	+5.273	<.001	.006	3	2
LUSC	RN7SKP83 →	+0.333	+5.093	<.001	.008	3	2
UCEC	OR13Z1P →	+0.172	+4.073	<.001	.004	3	2
SKCM	FAM243B →	+0.023	+4.640	<.001	.003	3	1
SKCM	H2AB3 →	+0.034	+5.647	<.001	<.001	3	1
SKCM	LINC01186 →	+0.773	+3.425	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

Exploration

SPANXB1 survival (RNA) · tumor vs normal (RNA) · all SPANXB1 data types