Across TCGA patient cohorts, SPANXA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 248 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPANXA1-associated GO terms across cancer lineages are Tonic smooth muscle contraction, Mitochondrial electron transport, ubiquinol to cytochrome c, and Nucleolar large rRNA transcription by RNA polymerase I. Each is linked with SPANXA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPANXA1-to-partner and partner-to-SPANXA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXA1→partner) and Y-score (partner→SPANXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
MESO	Tonic smooth muscle contraction →	+0.046	+0.191	.001	<.001	3	1
MESO	Mitochondrial electron transport, ubiquinol to cytochrome c →	+0.028	+0.215	.001	<.001	3	1
MESO	Nucleolar large rRNA transcription by RNA polymerase I →	+0.033	+0.246	<.001	<.001	3	1
MESO	Ribose phosphate biosynthetic process →	+0.013	+0.154	.005	.002	3	1
MESO	Short-chain fatty acid metabolic process →	+0.024	+0.165	.006	<.001	3	1
MESO	Cell fate commitment involved in pattern specification →	-0.065	-0.161	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 248 associations by consensus.

Exploration

SPANXA1 survival (RNA) · tumor vs normal (RNA) · all SPANXA1 data types